PharmaGuide
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(Application contains data on CEPHALOSPORINS only by default.
Complete Data is available through yearly subscriptions. Users
having complementary Scratch cards can use app with complete data
for One Month)
Instant and Predictive Search by:
Brand
Generic Name (e.g. Cefoperazone)
Contents (e.g. Cefoperazone and Sulbactam)
Therapeutic Category (e.g. Cephalosporins)
Interaction Checker:
Interaction Checker feature lets you quickly identify any interaction(s) among prescribed drugs.
You can select GENERICS as well as BRANDS in your country to check interaction.
Risk Factors
Information provided under Risk Factors include Contraindications Precautions and Risks in Pregnancy and Lactation for the relevant product.
Pregnancy: Risk cannot be ruled out.
Lactation: Contraindicated.
Contraindications: Severe respiratory depression severe obstructive lung conditions.
Precautions: COPD raised intracranial pressure impaired consciousness head injury bradyarrhythmia renal or hepatic impairment. Monitor for signs of respiratory depression. Brain tumour. Risk of tolerance and dependence. Elderly or debilitated patients.
Dosage (Alongwith Indications)
Fast Quick & Easy Access to Accurate Dosage in Specific Indications
The usual dosage are: Adults: Usually 1 gm daily by deep IM. slow IV inj over at least 2-4 min or IV infusion. Severe infections 2-4 gm as a single dose every 24 hrs. Children: Usually 20-50 mg/kg once daily by IM inj. slow IV inj over at least 2-4 min or IV infusion. Severe infections up to maximum 80 mg/kg daily. Doses over 50 mg/kg to be given by slow IV infusion over at least 30 minutes. Neonates: IM/IV: Postnatal age ≤ 7 days or > 7 days (body wt ≤ 2 Kg): 50 mg/kg/day given every 24 hrs. Postnatal age > 7 days body wt > 2 Kg: 50-75 mg/kg/day given every 24 hrs.
Administration
How to prepare and administer e.g. an Injectable
The drug may be administered by IV intermittent infusion over 10-30 min; final concentration for IV administration should not exceed 40 mg/mL. The drug has also been administered by direct IV push over 2-4 min. Inject deep IM into large muscle mass.
IM Injection: 250 mg/500 mg/1000 mg VIAL: To make concentration of 250 mg/mL add Water for Injection 0.9 mL in 250 mg vial; 1.8 mL in 500 mg vial; 3.6 mL in 1000 mg vial.
IV: 250 mg/500 mg/1000 mg VIAL: To make concentration of 100 mg/mL add Water for Injection 2.4 mL in 250 mg vial; 4.8 mL in 500 mg vial; 9.6 mL in 1000 mg vial.
Compatibility: Stable in D5W D10W NS Sodium bicarbonate 5% bacteriostatic water SWFI.
Stability: For IV infusion in NS or D5W solution is stable for 3 days at room temperature or 10 days when refrigerated.
Interactions
Amikacin Aminoglycosides Anticoagulants Gentamicin Kanamycin Neomycin Netilmicin Streptomycin Tobramycin Warfarin.
Adverse Effects
GI upset skin reactions blood dyscrasias. Rarely pseudomembranous colitis raised liver enzymes glycosuria oliguria haematuria bronchospasm phlebitis at inj site urinary and biliary precipitates pancreatitis.
Alternate Products
Quickly find Alternate Products - Just Click the Appropriate Button
Instant and Predictive Search by:
Brand
Generic Name (e.g. Cefoperazone)
Contents (e.g. Cefoperazone and Sulbactam)
Therapeutic Category (e.g. Cephalosporins)
Interaction Checker:
Interaction Checker feature lets you quickly identify any interaction(s) among prescribed drugs.
You can select GENERICS as well as BRANDS in your country to check interaction.
Risk Factors
Information provided under Risk Factors include Contraindications Precautions and Risks in Pregnancy and Lactation for the relevant product.
Pregnancy: Risk cannot be ruled out.
Lactation: Contraindicated.
Contraindications: Severe respiratory depression severe obstructive lung conditions.
Precautions: COPD raised intracranial pressure impaired consciousness head injury bradyarrhythmia renal or hepatic impairment. Monitor for signs of respiratory depression. Brain tumour. Risk of tolerance and dependence. Elderly or debilitated patients.
Dosage (Alongwith Indications)
Fast Quick & Easy Access to Accurate Dosage in Specific Indications
The usual dosage are: Adults: Usually 1 gm daily by deep IM. slow IV inj over at least 2-4 min or IV infusion. Severe infections 2-4 gm as a single dose every 24 hrs. Children: Usually 20-50 mg/kg once daily by IM inj. slow IV inj over at least 2-4 min or IV infusion. Severe infections up to maximum 80 mg/kg daily. Doses over 50 mg/kg to be given by slow IV infusion over at least 30 minutes. Neonates: IM/IV: Postnatal age ≤ 7 days or > 7 days (body wt ≤ 2 Kg): 50 mg/kg/day given every 24 hrs. Postnatal age > 7 days body wt > 2 Kg: 50-75 mg/kg/day given every 24 hrs.
Administration
How to prepare and administer e.g. an Injectable
The drug may be administered by IV intermittent infusion over 10-30 min; final concentration for IV administration should not exceed 40 mg/mL. The drug has also been administered by direct IV push over 2-4 min. Inject deep IM into large muscle mass.
IM Injection: 250 mg/500 mg/1000 mg VIAL: To make concentration of 250 mg/mL add Water for Injection 0.9 mL in 250 mg vial; 1.8 mL in 500 mg vial; 3.6 mL in 1000 mg vial.
IV: 250 mg/500 mg/1000 mg VIAL: To make concentration of 100 mg/mL add Water for Injection 2.4 mL in 250 mg vial; 4.8 mL in 500 mg vial; 9.6 mL in 1000 mg vial.
Compatibility: Stable in D5W D10W NS Sodium bicarbonate 5% bacteriostatic water SWFI.
Stability: For IV infusion in NS or D5W solution is stable for 3 days at room temperature or 10 days when refrigerated.
Interactions
Amikacin Aminoglycosides Anticoagulants Gentamicin Kanamycin Neomycin Netilmicin Streptomycin Tobramycin Warfarin.
Adverse Effects
GI upset skin reactions blood dyscrasias. Rarely pseudomembranous colitis raised liver enzymes glycosuria oliguria haematuria bronchospasm phlebitis at inj site urinary and biliary precipitates pancreatitis.
Alternate Products
Quickly find Alternate Products - Just Click the Appropriate Button
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